Eddie Brock attempts to reignite his career by interviewing serial killer Cletus Kasady, who becomes the host of the symbiote Carnage and escapes prison after a failed execution.

Within 24 hours, three people have been murdered in London, all by the name of Ben Lyk. Scotland Yard decides to gather together all the other Ben Lyks located in London until they can figure out who's after them and why.

Two agents from two different continents and two different mindsets, must work together to investigate when wreckage from a destroyed alien spacecraft has mysterious effects on humankind.